Sunday, September 13, 2009

Urticaria - Hives

Urticaria is a common skin problem characterized by development of itchy, transient weals (red patches) on the body. The number of weals and the severity of the condition is highly variable. These can also be associated with swelling of lips or any other part of the body.

    Urticaria occurs because of release of some mediators like histamine and serotinin in the body from immune cells resulting in a state of dilatation of blood vessels and increased leakiness of vessels resulting in collection of fluid in the skin; as this fluid gets reabsorbed the lesions disappear. The trigger for release of these mediators can be allergic or even non-allergic. Traditionally it was always considered that the main cause of urticaria was an immediate hypersensitivity reaction to an allergen that entered our body by way of ingested food or medications, inhaled pollen & dust etc or injected allergen like medications or insect bites. But now it is understood that very few of the urticaria are actually caused by a hypersensitivity reaction. In many of cases of urticaria the trigger cannot be identified.

          Sometimes urticaria can be associated with life threatening situration where because of laryngeal edema patients might suffer from choking sensation and if not treated urgently with appropriate medication it can result in death. So anytime there is a choking or breathing difficulty associated with urticaria it is very important to rush to a nearby hospital immediately. These situation are handled by injection of adrenaline.

          In case of a hypersensitivity reaction the triggers can be anything and subjective, so it’s very difficult to identify a trigger as anything can trigger it. Some foods are commonly implicated they include Foods with artificial coloring agents, Sea foods - fish, prawns, egg, peanuts, cashew nuts, chocolates, milk derivatives - cheese, panneer, khova, soya, Tomatoes, drumsticks, Strawberry etc.

Treatment of urticaria can be challenging as it is very difficult to identify the triggers. Treatment might involve long term use of antihistamines. Different individuals respond to different antihistamines. The optimal aim of treatment is to have reasonably good control of rashes with as minimum medicines as possible.

Many a times urticaria may go into remission but the duration of time required for tolerance to develop is unpredictable.

Wednesday, April 1, 2009

Psoriasis

Psoriasis is another chronic non-infectious skin condition characterized by occurrence of red or skin colour patches on various parts of body with scaling on them. The common sites of occurrence of psoriasis are back of elbow, front of knee, lower back, scalp, palms & soles but any body site may be involved.
Psoriasis occurs in various clinical forms, varying from occurrence of small scaling uniformly sized patches to geographic patches covering large areas of the body. Rarely almost entire skin surface may be involved with redness and scaling.
The cause of psoriasis is not known, but in some of the patients a family history is seen. It is caused due to some inflammatory mediators in the skin that cause increased rate of turnover of epidermal cells. There are several known triggers of psoriasis like infections, medications, stress etc. Alcohol and smoking have been found to worsen psoriasis.
Treatment options for psoriasis are several but till now drug has been found that can cure psoriasis. It can definitely be controlled with many of the treatment options available. The treatment option depends on the extent of body surface area involved, age of the patient, sex of the patient and the type of psoriasis that the patient is suffering.
Stress and anxiety are known to worsen psoriasis, worsening is also seen during the winter months. Patients with psoriasis need to understand that currently there is no cure available for it, but they need not loose heart there are several treatment options to control the disease. Don’t loose hope if your having psoriasis, it can be definitely controlled and you can lead a normal life.

Wednesday, January 14, 2009

Vitiligo

Vitiligo is a disorder characterized by appearance of white patches on various parts of the body. Vitiligo is an autoimmune disorder where the melanocytes which are the pigment producing cells in our skin are damaged. The exact cause for vitiligo is not known but several factors play an important role like genetic factors, stress, exposure to various chemicals etc.
Vitiligo is associated with lot of stigma, as colour forms an important part of appearance of an individual. Most of the stigma associated with vitiligo is unfortunate as it’s a simple non-contagious disorder. Patient suffering from vitiligo suffer from a severe depression and withdraw themselves from the society. This stress regarding the disease itself can cause worsening of vitiligo.
Vitiligo rarely can be associated with other autoimmune disorders like thyroid disorders, pernicious anaemia, alopecia areata etc. Vitiligo usually has an onset in 2nd to 3rd decades of life. The childhood vitiligo is also not very uncommon. The onset is most often related with a stressful event like loss of parent, loss of job etc.
Vitiligo appears as several clinical forms like
1. Focal vitiligo – appears as few white patches
2. Generalized vitiligo – where there is appearance of white patches all over body
3. Universal vitiligo – where almost entire colour the skin is lost
4. Segmental vitiligo – appears as localized white patches on one side of the body
5. Lip-Tip vitiligo – appears as white patches on lips and surrounding mouth and tip of fingers
In some of the cases the hair in the white patches can also become white. The characteristic feature of white patches in vitiligo is that the texture of the skin is entirely normal. The diagnosis of vitiligo is almost always clinical, rarely are some investigations required.
Treatment options for vitiligo are plenty, but as it is a chronic disease the treatment is prolonged and it may require treatment for 1-2 years, depending on the response. The various medical options for vitiligo include
1. For localized vitiligo – steroid ointments may be helpful or topical psoralen ointment or lotions can be used followed by exposure to sunlight.
2. For generalized vitiligo – systemic psoralens given with UVA or Sunlight is helpful. A good therapeutic option is Narrow-band UVB, with which the response is good and can be used in children. This phototherapy is given for 2-3 times/week and need to be continued for 3-6 months depending on the tolerance of the individual. It is a safe treatment without much adverse effects. For a vitiligo that is unstable and spreading a course of oral steroids for few weeks may be required to stabilise the disease.
3. Segmental vitiligo – doesn’t respond that well to treatment and is a very stable disease. Surgical management is a good option for segmental vitiligo.
4. Lip-tip vitiligo – It responds poorly to the medical line of treatment, surgical management is a good option provided the disease is stable.
5. Newer medical line of treatment includes use of immunomodulator creams like Tacrolimus, pimecrolimus. Beta-fibroblast growth factor lotion, lotion containing pseudocatalase and other enzymes. Excimer lasers can be used in management of vitiligo.
6. Diet – diet has no major influence on the course of vitiligo. But it is recommended that the patient reduces the intake of sour foods like lemon, orange, tomatoes etc.
7. Camouflaging with permanent make-up, tattoos can be used.
8. Advise for the patients suffering with vitiligo
Ø Have a positive attitude, don’t get depressed vitiligo can be treated
Ø Consult a good dermatologist, have patience as the treatment may be prolonged and in early part the response may not be dramatic
Ø Avoid injuries as vitiligo can develop at site of any types of trauma
Ø If the disease is widespread and sun exposed area is involved use a broad spectrum sunscreen to protect the skin.
Ø Follow the advice given by your doctor.
9. Surgical options for management of vitiligo require the disease to be stable. The type of procedure used depends on the shape of the patch, site and size. The various options used are
Ø Split-thickness skin grafting
Ø Miniature punch grafting
Ø Suction-blister grafting
Ø Melanocyte transplantation
Ø Dermabrasion
Ø Needling

Monday, December 29, 2008

Hair Loss

Hair loss is medically termed as alopecia, meaning loss of hair from any hair bearing area of the body.
Hair in primitive animals served an important function as it covered entire body surface and helped in maintaining body temperature, with the evolution of animals into human beings the hair coverage of the body declined gradually, in the end the hair coverage practically covering the scalp, eye brow, eye lashes. In human beings, function of hair is practically cosmetic as it forms an important part of appearance of a human being. Loss of hair causes significant psychological effect in many human beings.
Hair is appendage of the skin, which grows in a cycle. There are 3 phases in a hair cycle, namely
Anagen – this is the growing phase, the duration of this phase determines the length of the hair. Most of the hairs are in this phase.
Catagen – this is the stage where hair growth stops and it starts involuting. This phase lasts for few weeks
Telogen – this is the resting phase, here the hair which have stopped growing are held till they are shed off, this lasts for 2-3 months
Exogen – this is the phase of hair shedding
Every hair goes through this cycle, to keep producing the hair. Any disturbances in this hair cycle can cause significant hair loss. As some of the hairs are in a phase where they have to be shed, it is normal for some of the hairs to be shed daily. Normal average hair loss daily is 75-100 per day.
Hair loss is a very common problem for which a patient consults a dermatologist. In a broad way the cause of hair loss is most often simple, it depends the loss of hair is in a patch or it is diffuse occurring all through the scalp. Causes of these 2 different types of hair loss are varied.
Diffuse hair loss – this is much more common than the patchy hair loss. Most of the patients who come for consultation complain of diffuse hair loss. This hair loss can occur in a patterned manner in both the sexes; this is what is called as male-pattern and female-pattern baldness. The pattern of hair loss differs in males & females, in males it starts with recession of hairline from the front, while in females it starts as widening of central partening or loss of density of hair on the vertex i.e top of the head. This patterned hair loss is genetically determined process and is a gradually progressive condition.
The next common causes of hair loss particularly in a woman are Iron deficiency anaemia, thyroid disorders, malnutrition etc; this is termed as Chronic telogen effluvium. In some cases any acute sever illness like fevers (malaria, typhoid etc.), surgery, trauma, post-partum, severe stress can be followed by a bout of hair loss about 2-3 months following the event, this is called as Acute telogen effluvium. Some of the medications can also be a cause of hair loss; the common medications that can be a cause of hair loss are anti-cancer drugs, heparin, anti-thyroid drugs, retinoids etc.
The next form of hair loss is the patchy form this can be divided into scarring or non-scarring depending on the presence of opening of hair roots (hair follicles). The various causes of non-scarring patchy alopecia are:
Alopecia areata, this is a common cause of non-scarring patchy hair loss more so among children. It is an autoimmune disorder i.e the body starts damaging its own organ in this case the hair. It is most often a self-limiting disorder but sometimes when it is rapidly spreading or involves extensive areas it responds poorly to treatment. It can be precipitated by stress. There are several treatment options for managing it properly.
In children another common cause of patchy hair loss is the fungal infections of the hair on scalp i.e tinea capitis. This can present in several ways, like a scaling patch on the scalp or a patch of hair loss with broken hair at the surface of the hair root opening.
Another not so common cause of hair loss is the trichotillomania, which is an obsessive compulsive disorder in which the patient’s pulls off his/her own hair resulting in patches of hair loss. This form shows a characteristic tuft of broken and twisted hair.
Traction alopecia is a form of alopecia commonly seen at the front of the hair occurring due to some of the hair styles that exert an excessive pull on the hair.
Next form of hair loss is the scarring type, in which there is destruction of the hair roots, resulting in patches of hair loss that is permanent. It can occur because of several skin disorders like discoid lupus erythematosus, lichen planus, folliculitis decalvans, severe fungal infections like kerion, favus etc. Severe bacterial infections like recurrent folliculitis, furuncles etc. The causes of scarring alopecia are plenty. Management of scarring alopecia is difficult and most often it is permanent.
In addition to the above mentioned causes there are several more causes of hair loss.
Hair Care measures:
1. Hairs are a pure protein structure so a good diet is necessary for good hair.
2. Don’t use too harsh shampoos or cosmetics on hair.
3. Never comb hair when they are wet.
4. Don’t use shampoo’s more than 2 times in a week.
5. Don’t undergo procedures like hair straightening, curling etc.
Management of Hair loss: depends on its cause; there are several treatment options available for the various forms of hair loss. Whatever the treatment used it takes time for the response to be obtained as the hair grow in a cycle and the dynamics of the hair cycle need to be altered to get response, and it takes time for these things to happen. So, any treatment used for hair loss should be given a trial for at least 2 months before thinking of any response.

Wednesday, September 10, 2008

Acne Vulgaris - Pimples

Acne (pimples) are a commonly seen in the age group of 15 to 30 years. They are associated with lots of stress and anxiety among the patients as they can heal with scarring and hyperpigmentation. Acne are a result of occlusion of the sebaceous glands present on face, chest and upper back. The reason for this occlusion are many like increased activity of these glands during this age group, obstruction to the duct of the gland etc etc.

Acne present with variety of lesions like black heads (open comedones), white heads (closed comedones), red raised papules, pus filled lesions etc. Acne may be precipitated by several factors like stress, anxiety, hormonal levels, some medicines etc. Role of diet in acne is controversial, previously it was believed that diet plays an important role in acne, but as off now there is no scientific evidence that diet plays any role in acne. But, still if some patients can associate some foods with worsening of acne they can avoid them. Most important exacerbating factor is stress.
Acne may be associated with a great degree of psychological disturbances like anxiety, depression etc. So what can we do to get rid of acne. Hmmm...........first n foremost acne is not a disease so we can just control it, time will cure them. After some age acne stop coming. So, the main aim of treatment is to keep them under control and to prevent scarring like pigmentation, pitted scars etc. There are several treatment options for managing acne including antibiotic creams, benzoyl peroxide creams, retinoid creas. In case they are more severe several oral medications like oral antibiotics, oral retinoids can be tried. Provided u take proper care of your acne it shouldnt be a big problem. So what are the things that you can do to help your acne.

  • FIRST & FOREMOST - STOP WORRYING ABOUT THEM because that by itself can worsen your acne,
  • Second - dont pick at your acne as that is likely to cause scarring,
  • Third - wash your face regularly and avoid using oily make-up's go for lighter non-oily make ups,
  • Fourth - Dont use too much of moisturisers,
  • Fifth - dont try any home remedy on them, consult a good dermatologist and he can surely help you.
  • Sixth - Food scientifically has no role in acne, so you need not stop eating things that you like.

Acne respond slowly to treatment you got to have patience to follow what your doctor has advised you. Avoid getting into scarring, once scarring is developed treatment is prolonged and u may require chemical peeling, laser treatment etc. So, dont allow your acne to stop you from enjoying your life ................it can be managed most often with simple treatments.

Tuesday, September 9, 2008

Dermatology

Dermatology is a branch of medicine that deals with disorders of skin, hair and nail. This is the branch that deals with the largest organ of our body, the skin. Since ancient times men and women have been obsessed with looking good, of which good skin forms a fundamental requirement. Other than looking good, a healthy skin has been considered as an integral part of good health.

Skin because of its location is at an interface between the internal & external environment, peforming several important function in maintaining normal body functions including temperature regulation, maintaining water & electrolyte balance, defense against physical & chemical agents..................to name just a few of many. And not to forget the role it plays in psychosocial well-being of humans.

Becasue of it being exposed, any skin problem is associated with lots of stress & anxiety. Even a minor skin problem causes lots of anxiety among patients because of its visibility. But as they say every problem has a solution, similarly every skin problem has a solution too. Thats where the role of dermatologist comes.

I would like to help anyone who has any queries related to skin, hair and nail. I will surely be answering to your questions so do feel free to ask...............